PENGARUH PEMBERIAN SUPLEMEN VITAMIN B12
TERHADAP SERUM VITAMIN B12 DAN HEMOGLOBIN
ANAK PRASEKOLAH
 Zulhaida Lubis1
, Hardinsyah2, Hidayat Syarief3
, Fasli Jalal4
, dan Muhilal5


 1
Program Doktor PS GMK SPS IPB
 2
Dept. Gizi Masyarakat FEMA IPB
 3
Dept. Gizi Masyarakat FEMA IPB
 4
Dirjen Peningkatan Mutu Pendidik dan dan Tenaga Kependidikan Depdiknas dan Fak.
Kedokteran Univ. Andalas Padang
 5
Fak. Kedokteran UNPAD Bandung


ABSTRACT
This research aimed to analyze prevalence of vitamin B12 deficiency and anemia,
and effects of vitamin B12 suplement on vitamin B12 serum and hemoglobin of
preschool children. A randomized controlled trial of 32 preschool children (4-6
year) for 6 months was appliad. Subjects divided in to 2 groups, treatment group
(received 10 μg vitamin B12 syrup daily) and control group (placebo).
Consentration of vitamin B12 serum and hemoglobin of children was measured
before and after their intervention. The results of research indicate that prevalence
of vitamin B12 deficiency and anemia among preschool children was 24,1% and
41.4% respectively. After getting vitamin B12 suplement, vitamin B12 deficiency
of treatment group decreased from 26.7% to 0.0%, while in the control group
increase from 21.4% to 28.6%. Vitamin B12 suplement influenced vitamin B12
serum level significantly ( p < 0.05). Vitamin B12 serum increase at the treatment
group148.4 ± 110.9 pg/ml and only 3.7 ± 12.8 pg/ml at control group. Hemoglobin
concentration was influenced vitamin B12 suplement especially to anemia
preschool children.

PENDAHULUAN

Usia prasekolah adalah bagian dari
periode usia dini yang mengalami proses
pertumbuhan dan perkembangan pesat dalam
siklus kehidupan dan turut menentukan
kualitas manusia. Separuh perkembangan
kognitif berlangsung dalam kurun waktu
antara konsepsi sampai usia 4 tahun, dan
30% berlangsung pada usia 4-8 tahun.
Sehingga pada periode ini anak sangat
memerlukan gizi yang memadai agar
kapasitas otak yang terbentuk dapat
maksimum (Gutama 2004).
disini aja kali ya???